The German side claimed a 2-2 draw in the first leg in Ukraine and are desperate to proceed to keep their season alive. Both teams refused to change their fast style of play in the first leg which resulted in a 4 goals scored, both on each side. Borussia are hoping defender Mats Hummels can recover in time for the match as he is suffering from a flu ever since the first leg in Ukraine.
The only injury concern for Shakhtar is Dmytro Chygrynskiy, who did not travel to Germany with his team. Like Dortmund, Shakhtar's second- and third-best central defenders are just as capable as their injured star.
"I have read that it would be a lost season if we don't go through," said Dortmund manager Jurgen Klopp. "I think that's very harsh."
"We have a big opportunity to finish second in the Bundesliga: we wouldn't have dreamt of that three years ago. It is a very, very important match for us because we have the opportunity of reaching something new; the quarter-finals in the Champions League."
Projected starting lineups (left to right)
Borussia Dortmund (4-2-3-1): Roman Weidenfeller; Marcel Schmelzer, Felipe Santana, Neven Subotic, Lukasz Piszczek; Ilkay Gündogan, Sebastian Kehl; Marco Reus, Mario Götze, Jakub Blaszczykowski; Robert Lewandowski
Shakhtar Donetsk (4-2-3-1): Andriy Pyatov; Razvan Rat, Yaroslav Rakitskiy, Oleksandr Kucher, Darijo Srna; Tomas Hübschman, Fernandinho; Taison, Henrikh Mkhitaryan, Alex Teixeira; Luiz Adriano